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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15718 | Latanoprost acid | GPR | |
Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about low... | |||
T37214 | 5-trans Latanoprost (free acid) | ||
Latanoprost is an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drug. Latanoprost is an isopropyl ester, a prodrug form which is converted to latanoprost (free acid) by endog... | |||
T37933 | 15-keto Latanoprost (free acid) | ||
15-keto Latanoprost is a potential metabolite of latanoprost when administered to animals. 15-keto Latanoprost is also one of the common minor impurities found in commercial preparations of the bulk drug compound. Althou... | |||
T37931 | 15(S)-Latanoprost | ||
15(S)-Latanoprost is an analog of latanoprost in which the hydroxyl at carbon 15 is inverted relative to latanoprost. The IC50 values for the free acid forms of latanoprost and 15(S)-latanoprost were determined to be 3.6... | |||
T37943 | 17-phenyl trinor Prostaglandin F2α isopropyl ester | 17-phenyl trinor Prostaglandin F2α isopropyl ester | |
17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prod... | |||
T37627 | Latanoprost ethyl amide | ||
Latanoprost ethyl amide (Lat-NEt) is a latanoprost analog in which the C-1 carboxyl group has been modified to an N-ethyl amide. Prostaglandin esters have been shown to have ocular hypotensive activity. Prostaglandin N-e... | |||
T37948 | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | 17-trifluoromethylphenyl-13,14-dihydro trinor Prostaglandin F2α | |
A number of 17-phenyl trinor prostaglandin F2α(17-phenyl trinor PGF2α) derivatives have been approved for the treatment of glaucoma.1,2,3Of these, the ones wherein the 13,14-double bond has been hydrogenated retain relat... | |||
T37947 | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | 17-trifluoromethylphenyl trinor Prostaglandin F2α methyl ester | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor PGF2α is an analog of PGF2α that shares the meta-triflu... | |||
T37777 | 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide | 17-trifluoromethylphenyl trinor Prostaglandin F2α ethyl amide | |
Prostaglandin F2α (PGF2α), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. 17-trifluoromethylphenyl trinor Prostaglandin F2α (17-trifluoromethylphenyl trinor PGF2... |